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Fine lines & wrinkles

Peptide-4 Pro-collagen

Expression lines, Adults

15 ml - 0.5mg/100g

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A biomimetic collagen booster that targets expression lines on the forehead, eye contour area and mouth, where skin is most demanding and where wrinkles set in. The ideal solution for reducing frown lines.

  • Fragrance-free
  • Made in France
  • No artificial colouring agents
  • Silicone-free
  • Tested under dermatological control
  • Vegan
  • Redensifies

    This peptide, naturally present in the skin, stimulates the synthesis of collagen and other dermal components essential for skin density and firmness.

  • Smooths wrinkles

    Visibly reduces expression lines thanks to its collagen boosting action.

Is this care suitable
for your skin?

  • When

    Our recommendation: use for 8 weeks as a targeted treatment for expression lines.

  • Where

    Apply to the entire face, concentrating on wrinkles. Apply to dry, thoroughly cleansed skin.

  • How

    Squeeze the base of the bottle and apply 2 drops to the tips of the fingers per area of concern. Gently smooth and press onto the skin. i.e., 2 drops per area for wrinkles on the forehead, eye contour area and mouth.

Do not use more than 2 pure active ingredients at a time. If you are using 2 active ingredients, you may apply one after the other.

The efficacy of this highly purified and perfectly dosed active ingredient is scientifically proven to help diminish facial expression lines.

We have added additional ingredients to this active: their exclusive role is to ensure the product’s stability and ability to penetrate the skin (In-Skin patent). Nothing more, nothing less.
For more information on the composition of this product, click:

AQUA/WATER/EAU

What it is?

Water contained in Isodermic Water.

What’s the point?

Contributes to the Isodermic Water patent.
NAOS has designed a perfectly defined water, meeting the three fundamental criteria for physiological fluids: pH, oxidation resistance, and concentration of mineral salts.
It optimises cellular functioning and preserves the balance of healthy skin.

Components contributing to this patent: aqua/water/eau, disodium adenosine triphosphate, carnosine, laminaria digitata extract.

How do you get it?

Mineral origin.

PROPANEDIOL

What it is?

Polyol.

What’s the point?

Contributes to the In-Skin patent.
This patented complex optimises the diffusion of the active ingredient in the skin for targeted action.

How do you get it?

Biotechnology.
Biotechnology uses biological processes, including natural fermentation, to obtain ingredients.

ALCOHOL

What it is?

Wheat alcohol.

What’s the point?

Contributes to the In-Skin patent.
This patented complex optimises the diffusion of the active ingredient in the skin for targeted action.

How do you get it?

Biotechnology.
Biotechnology uses biological processes, including natural fermentation, to obtain ingredients.

DISODIUM PHOSPHATE

What it is?

Sodium derivative.

What’s the point?

Stabilising: helps adjust the product’s pH.

How do you get it?

Component naturally found in the skin, of mineral origin.

GLYCERIN

What it is?

Glycerin.

What’s the point?

Humectant: maintains the skin’s moisture level.

How do you get it?

Component naturally found in the skin, extracted from vegetable oil.

CAPRYLOYL GLYCINE

What it is?

Lipoamino acid.

What’s the point?

Stabilising: contributes to the product’s homogeneity or stability.

How do you get it?

Obtained by synthesis from fatty acid extracted from vegetable oil, and synthesised glycine.

CAPROOYL TETRAPEPTIDE-3

What it is?

Lipopeptide.

What’s the point?

Anti-wrinkle: provides the skin with tone and firmness.

How do you get it?

Synthesis

To select an ingredient, NAOS can call on synthesis in order to:
– reconstitute a natural molecule without having to extract it from a plant and thus better respect biodiversity,
– obtain a pure, perfectly defined ingredient.

POTASSIUM PHOSPHATE

What it is?

Potassium derivative.

What’s the point?

Stabilising: helps adjust the product’s pH.

How do you get it?

Component naturally found in the skin, of mineral origin.

SODIUM LACTATE

What it is?

Lactic acid derivative.

What’s the point?

Contributes to the In-Skin patent.
This patented complex optimises the diffusion of the active ingredient in the skin for targeted action.

How do you get it?

Component naturally found in the skin, obtained by biotechnology.
Biotechnology uses biological processes, including natural fermentation, to obtain ingredients.

LEUCONOSTOC/RADISH ROOT FERMENT FILTRATE

What it is?

Black radish extract.

What’s the point?

Stabilising: contributes to the product’s homogeneity or stability.

How do you get it?

Biotechnology.
Biotechnology uses biological processes, including natural fermentation, to obtain ingredients.

XANTHAN GUM

What it is?

Xanthan gum.

What’s the point?

Gelling: provides the texture with consistency.

How do you get it?

Biotechnology.
Biotechnology uses biological processes, including natural fermentation, to obtain ingredients.

SALIX NIGRA (WILLOW) BARK EXTRACT

What it is?

Black willow extract.

What’s the point?

Stabilising: contributes to the product’s homogeneity or stability.

How do you get it?

Black willow bark extraction.

SODIUM HYDROXIDE

What it is?

Sodium derivative.

What’s the point?

Stabilising: helps adjust the product’s pH.

How do you get it?

Component naturally found in the skin, obtained by synthesis.

To select an ingredient, NAOS can call on synthesis in order to:
– reconstitute a natural molecule without having to extract it from a plant and thus better respect biodiversity,
– obtain a pure, perfectly defined ingredient.

LAMINARIA DIGITATA EXTRACT

What it is?

Brown algae extract.

What’s the point?

Contributes to the Isodermic Water patent.
NAOS has designed a perfectly defined water, meeting the three fundamental criteria for physiological fluids: pH, oxidation resistance, and concentration of mineral salts.
It optimises cellular functioning and preserves the balance of healthy skin.

Components contributing to this patent: aqua/water/eau, disodium adenosine triphosphate, carnosine, laminaria digitata extract.

How do you get it?

Laminaria algae extraction.

CARNOSINE

What it is?

Peptide.

What’s the point?

Contributes to the Isodermic Water patent.
NAOS has designed a perfectly defined water, meeting the three fundamental criteria for physiological fluids: pH, oxidation resistance, and concentration of mineral salts.
It optimises cellular functioning and preserves the balance of healthy skin.

Components contributing to this patent: aqua/water/eau, disodium adenosine triphosphate, carnosine, laminaria digitata extract.

How do you get it?

Component naturally found in the skin, obtained by synthesis.

To select an ingredient, NAOS can call on synthesis in order to:
– reconstitute a natural molecule without having to extract it from a plant and thus better respect biodiversity,
– obtain a pure, perfectly defined ingredient.

DISODIUM ADENOSINE TRIPHOSPHATE

What it is?

Nucleotide (ATP).

What’s the point?

Contributes to the Isodermic Water patent.
NAOS has designed a perfectly defined water, meeting the three fundamental criteria for physiological fluids: pH, oxidation resistance, and concentration of mineral salts.
It optimises cellular functioning and preserves the balance of healthy skin.

Components contributing to this patent: aqua/water/eau, disodium adenosine triphosphate, carnosine, laminaria digitata extract.

How do you get it?

Component naturally found in the skin, obtained by biotechnology.
Biotechnology uses biological processes, including natural fermentation, to obtain ingredients.

DEXTRAN

What it is?

Sugar macromolecule.

What’s the point?

Stabilising: contributes to the product’s homogeneity or stability.

How do you get it?

Biotechnology.
Biotechnology uses biological processes, including natural fermentation, to obtain ingredients.

Of the 30,000 ingredients approved for use in cosmetics, our formulation charter only includes 150 to keep only those that respect your skin.

Find out more
  • How do I know if I have expression lines?

    Expression lines are the first wrinkles to appear on the face. They are caused by the repeated facial movements (43 fascial muscles and around 10,000 contractions per day!) that express our different emotions. They include wrinkles on the forehead (horizontal), frown lines (between the eyebrows), crow’s feet (beside the eyes), bunny lines (from wrinkling the nose), and smoker’s lines or barcode wrinkles (around the mouth).

  • What is collagen?

    Collagen is a protein found naturally in every structure of the body, including the skin. It makes up 30–35% of the protein in the body and gives these tissues cohesion, elasticity and regenerative abilities. Skin collagen is found in the dermis and is what keeps our skin plump however begins to break down with repetitive movement (expression lines) and over time with age and certain lifestyle factors (smoking, pollution, UV exposure, etc.)

  • Pure Active: how is this different from a serum?

    In terms of the way it is used, Pure Actives are applied like a serum: to clean skin before your face cream, to provide a specific action.
    But, unlike a serum, our Pure Actives only contain a single, perfectly dosed, active molecule, which precisely targets a skin issue. This means that they are ultra-safe, since there’s no risk of a cocktail effect (piling up different active ingredients). And our INSkin™ patent helps it to penetrate down to where it needs to be in the skin.

  • Pure Active: should I apply it before or after my face cream?

    Always before your moisturising cream, but most importantly, always on clean skin. Thanks to their drop-by-drop bottles, Pure Actives are applied in small quantities, where they are needed (see the detailed instructions for each product).

  • What is the maximum number of Pure Actives that I can apply to my skin?

    We recommend applying no more than 2 Pure Actives at once to your face (1 Pure Active after the other, to clean skin before applying your face cream). In most cases, the best solution is to treat one problem at a time with a Pure Active. If you apply multiple active substances on your skin there is a risk of over-treating it.

  • How long should a Pure Active be used for?

    Pure Actives should be used like a “course of treatment”, for between 3 and 8 weeks depending on the active ingredient and the benefit in question. That’s why we package them in small anti-UV containers suited to short-term use. To ensure they stay effective, you should store them away from heat and light, and for no more than 6 months. You’ll find usage instructions for each Pure Active on the product pages on the site.

  • What is the difference between Pure Skincare and Pure Actives?

    Pure Skincare products do not contain any active ingredients, to take care of skin every day, without needlessly irritating it. Pure Actives offer a targeted action to treat skin problems when necessary (1 Pure Active = 1 skin issue). Healthy skin with no particular issues does not need Pure Actives.

  • Do your products contain fragrances?

    Our Pure Actives do not contain fragrances, nor do some of the other care products such as the Moisturising Eye Contour Fluid, the Melting Exfoliating Gel and the Express Purifying Mask. The majority of our Pure Skincare products are very lightly scented to make them pleasant to use while being kind to skin. We carefully select our fragrances, which we create ourselves, and make sure they are free from allergens and sensitising substances.

  • Are your products tested on animals?

    No, in accordance with the applicable European cosmetics regulations, our products and the ingredients they contain are not tested on animals. Toxicology experts have evaluated our formulas’ perfect tolerance. And, of course, our products are tested under dermatological and ophthalmological supervision if necessary.

  • Do your products contain preservatives?

    In order to protect our formulas from contamination, we use the necessary amount of natural preservatives (black radish extract, potassium sorbate or capryloyl glycine). We also use airless bottles, pumps and tubes to limit the risk of contamination, and therefore the quantity of preservatives.

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